Experiments with silver-cysteine nanoparticles and TRAIL-conjugated silver nanoparticles coated with PEG (AgCTP NPs) showed that AgCTPNPs exhibited apoptotic effects in HT-29 colon cancer cell line in vitro with substantial differences in the expression levels of Bax, Bcl-2, and cleaved PARP protein[110]. The gene discussed is TNFSF10; the disease is colonic neoplasm.