Similarly, data about the nuclear β-catenin accumulation in parathyroid tumors are controversial; nonetheless, the WNT/β-catenin pathway can play a role in parathyroid cell biology as its activation by lithium chloride inhibited the expression of the embryonic transcription factor TBX1 (37) and increased the aberrant expression of miR-372 in PAds-derived cells (38). This evidence concerns the gene TBX1 and tumor of parathyroid gland.