The number of individuals diagnosed with osteoporosis is significantly higher for homozygous individuals compared with heterozygous or wild‐type individuals (odds ratio [OR] 3.33) after adjusting for other parameters, including alcohol consumption history.(23) The ALDH2*2 allele is also significantly associated with hip fracture (OR 2.48) and osteoporosis (OR 2.04) when alcohol consumption was not considered.(24). The gene discussed is ALDH2; the disease is osteoporosis.