TBX1 and neoplasm: We explored the relationship between CafS and tumor invasion-related pathways to further understand the mechanism of tumor process, we found CafS was significantly positive correlated with these tumor invasion-related, DNA damage-related and metabolism-related signaling pathways (EMT: r = 0.87, p = 1.77e-268; Coagulation: r = 0.82, p = 7.12e-209; Angiogenesis: r = 0.82, p = 3.19e-215; Hypoxia: r = 0.53, p = 1.09e-63; Uv-response-down: r = 0.60, p = 1.24e-86; respectively; Figures 6B–F).