GPR84 and neoplasm: To further explore the effect of GPR84Y370H variant on GCs, we constructed the GPR84Y370H overexpressed (shown as GPR84WT/mut) and GPR84 overexpressed (shown as GPR84WT/WT) stable cell lines in KGNs (human granulosa-like tumor cell line), while the GPR84WT/WT group was regarded as the control (Figures 5A, B).