Twenty-seven HCC-specific TFs were listed in the TiED database, including ARID3A, BACH1, BATF, BCL11A, CEBPB, CTCFL, EGR1, ESR1, FOS, FOXA1, FOXA2, GATA1, GATA2, GATA3, HNF4A, HNF4G, IRF4, MAFF, MAFK, MTA3, MYBL2, MYC, PAX5, RUNX3, TEAD4, TFAP2A, and TFAP2C. Here, FOXA1 is linked to hepatocellular carcinoma.