Twenty-seven HCC-specific TFs were listed in the TiED database, including ARID3A, BACH1, BATF, BCL11A, CEBPB, CTCFL, EGR1, ESR1, FOS, FOXA1, FOXA2, GATA1, GATA2, GATA3, HNF4A, HNF4G, IRF4, MAFF, MAFK, MTA3, MYBL2, MYC, PAX5, RUNX3, TEAD4, TFAP2A, and TFAP2C. This evidence concerns the gene CTCFL and hepatocellular carcinoma.