Variant rs148698650 detected in LDLR has been linked to alterations in lipid profile according to ClinVar, rs1800206 in PPARA has been associated with lipid-altered phenotypes in three studies (Vohl et al., 2000; Tai et al., 2002; Robitaille et al., 2004), and rs748231262 in SCARB1 has one report in an Argentinian study of familial hypercholesterolemia (Corral et al., 2018). The gene discussed is PPARA; the disease is familial hypercholesterolemia.