SOX9 and Alzheimer disease: Not many studies have looked in the relationship of SOX9 with AD, however, in their recent study Xia et al. show that through targeting SOX9, miR-22-3p could inhibit apoptosis of Aβ-treated HT22 cells in vitro, in addition to improving Aβ deposition and consequently enhancing behavior in mice through the Morris water maze tests [10].