SIRT1 and preeclampsia: The results showed that the AUC value of serum SIRT1 expression combined with uterine artery hemodynamic parameters (AUC = 0.776) was higher than that of serum SIRT1 expression (AUC = 0.750) and the uterine artery hemodynamic flow velocity peak-to-trough ratio (AUC = 0.704) (Figure 6), suggesting that serum SIRT1 expression combined with uterine artery hemodynamic parameters has a high diagnostic value for the severity of preeclampsia.