EZH2 and acute kidney injury: Numerous studies have confirmed that macrophages are recruited from the circulatory system to the injured site to participate in inflammatory reactions during AKI, which is strongly related to the prognosis of AKI, and the migration ability of macrophages is an important evaluation index 6, 29, 42.This results confirmed that EZH2 deficiency reduced apoptosis of renal TECs and inhibited the tubulointerstitial inflammation characterized by macrophage infiltration.