Interestingly, in RAW cells free cytosolic parasites are surrounded by LC3 protein and other markers of selective autophagy such as Ubiquitin, SQSTM1/p62 and NDP52, features that were observed in lesser extension in autophagy-deficient cells, indicating that this process contributed to control the infection by elimination of intracellular amastigotes [353]. The gene discussed is SQSTM1; the disease is infection.