Genes associated with glucocorticoid receptor signaling, which is a target for corticosteroid-based therapy in EoE patients (36), and aryl hydrocarbon receptor pathway, which has been linked to proton pump inhibitor-mediated inhibition of epithelial proliferation and IL-13 signaling (37), were also identified in EoE-enriched clusters (Figure 6B; Table 1). Here, NR3C1 is linked to eosinophilic esophagitis.