NPR3 and atherosclerosis: Woodard and colleagues applied three types of 64Cu-CANF-comb nanoprobes to assess the in vivo PET imaging of NPR-C, which is expressed on atherosclerotic plaques, and found that the 25% 64Cu-CANF-comb shows the best NPR-C targeting specificity as well as sensitivity in Apoe-/-mice, suggesting the 25% 64Cu-CANF-comb as a good PET imaging agent to detect atherosclerosis 103.