However, despite of the fact that the majority of findings from recent studies using peripheral markers point toward a higher proinflammatory state in people with PTSD, a study using post-mortem brains of people with PTSD intriguingly found lower levels of IL-1α gene expression in the prefrontal cortex (PFC) compared to controls (Morrison et al., 2019). The gene discussed is IL1A; the disease is post-traumatic stress disorder.