This variant is found in exon 8 of a gene adjacent to DRD2 (ANKK1: Ankyrin repeat and kinase domain containing 1), it changes glutamate to lysine at codon 713 (Céspedes, 2017) and has been linked to a lower receptor density (Blum et al., 2018), self-regulation disorders, excessive consumption of food and loss of control over dietary intake (Ariza et al., 2012) and obesity and addiction (McDonell et al., 2018). The gene discussed is DRD2; the disease is Obesity.