GSDMB and neoplasm: To further identify the potential functions of GSDMB, we analyzed the pan-cancer expression of GSDMB, including mRNA expression, clinical survival and prognosis, immune cell infiltration, and potential signal pathways from The Cancer Genome Atlas (TCGA) database to explore the potential mechanism of tumorigenesis and tumor inhibition among different cancer species (9, 22) (Figure S1).