HIF1A and hepatocellular carcinoma: In this study, the AFP, CA199, CEA and HIF-1 indexes of the two groups decreased after treatment, and the AFP, CA199, CEA and HIF-1 indexes of group A were significantly lower than those of group B, suggesting that apatinib combined with camrelizumab Antibiotics can further reduce the level of serum tumor markers in HCC patients.