GI toxicity:Nausea: 33% vs 46%Dysphagia: 47% vs 15%Anorexia: 37% vs 31%Vomiting: 30% vs31%Diarrhoea: 0 vs 23%*Hematologic toxicity:Leukopenia: 64% vs 78%Anaemia: 0 vs 15%Thrombocytopenia: 23% vs 54%*Platelet transfusion: 17% vs 46%*RBC transfusion: 50% vs 39%WBC: -0.57 ± 2.22 vs -2.61 ± 2.27*Hb: +0.23 ± 1.04 vs -0.7 ± 1.89Platelet: -0.49 ± 0.64 vs -1.37 ± 0.96*. This evidence concerns the gene GSTM1 and anemia.