Results of molecular function enrichment analysis were enriched in epidermal development, hemidesmosome assembly, skin development, molting cycle, hair cycle, O-glycan processing, extracellular matrix organization, hair follicle maturation, multicellular organism homeostasis, cornification, etc. Results of KEGG enrichment analysis were enriched for IL-17 signaling pathway, mucin-type O-glycan biosynthesis, amoebiasis, TNF signaling pathway, ECM-receptor interactions, Staphylococcus aureus infection, viral proteins interacting with cytokines and cytokine receptors, etc. The gene discussed is IL17A; the disease is amebiasis.