Fluorescence intensity of MHI-148 was assessed in SNU-739 cells after transfection of specific siRNAs against ABCs including ABCG2, ABCB1 and ABCC1, which were reported to be able to transport numerous diverse chemical substrates out of cells and were associated with drug efflux in HCC cells. This evidence concerns the gene ABCC1 and hepatocellular carcinoma.