To explore whether SLC transports participated in the uptake of MHI-148 into HCC cells, the fluorescence intensity of MHI-148 was assessed in SNU-739 after transfection of specific siRNAs against six kinds of SLC transporters which are mainly localized in hepatocytes (including OATP1B3, NTCP, OATP1B1, OAT2, OATP2B1 and OCT1). The gene discussed is SLC22A7; the disease is hepatocellular carcinoma.