Additionally, the mRNA expression of ACADSB, CHAC1, and TFAP2A were also significantly upregulated in ccRCC cell line 786-O, while the CHAC1 was downregulated but ACADSB and TFAP2A were upregulated in another ccRCC cell line OS-RC-2 (Figures 10F–J). The gene discussed is CHAC1; the disease is nonpapillary renal cell carcinoma.