AKT1 and myocardial infarction: Cheng Songyi (84) has found that astragaloside A can activate PI3K/Akt pathway, increase the expression level of vascular endothelial growth factor (VEGF), promote angiogenesis after myocardial infarction and reduce heart damage by interfering with myocardial infarction rats and human umbilical vein endothelial cell (HUVEC) with different doses of astragaloside A. Leng et al. (85) used ginsenoside Rg1 to intervene in the model of isoproterenol-induced acute myocardial ischemia.