These cells expressed high levels of chemoattractants (CCL3, CCL4, and XCL1) of other immune cells that can exacerbate NASH-associated inflammation, and overexpressed IL12 and IL18 receptors, a fact that suggests they are more prone to be activated and participate in the recruitment of CD8+ T cells (45). Here, CD8A is linked to metabolic dysfunction-associated steatohepatitis.