In CD8+ T cells, we found higher proportions of IFN-γ producing cells in both the T-LGLHIGH and the T-LGLLOW IBM patient groups relative to HC (median=57.1% and 47.1% vs 19.5% respectively, P<0.0001 and P= <0.0013; Figure 7A). Here, IFNG is linked to inclusion body myositis.