Other widely used biomarkers, such as neutrophil gelatinase-associated lipocalin (NGAL), kidney injury molecule-1 (KIM-1), urinary tissue inhibitor of metalloproteinase 2 (TIMP-2) paired with urine insulin-like growth factor binding protein 7 (IGFBP-7) ([TIMP-2]·[IGFBP-7]), etc., are similarly insufficient for describing DI-AKI and vary amongst DI-AKI. This evidence concerns the gene TIMP2 and acute kidney injury.