QPCTL and central nervous system cancer: To explore the importance of QPCTL in glioma cells, we checked both the DepMap database and the BioGRID database, as shown in Supplementary Table 1 (data from BioGRID) and Supplementary Table 2 (data from DepMap); both CRISPR databases show that QPCTL is the essential gene for glioma cells’ proliferation.