There were no significant differences between the two groups (KTRs with or without a breakthrough infection) with respect to age, sex, Charlson Comorbidity Index, eGFR, CRP, WBC, lymphocyte counts, CMV and BK viremia, and the type of immunosuppression (data not shown) and the numbers of RBD-specific IgG- secreting memory B cells (Figure 6C) and serum neutralization capacity for Omicron BA.5 (Figure 6D). The gene discussed is CRP; the disease is infection.