A retrospective study based on 407 patients found that CD64 had the highest diagnostic value for the development of SIRS after ureteroscopy holmium laser lithotripsy compared to PCT versus CRP, with an area under the ROC curve of 1.0 at 2 hours, 6 hours, and 1 day postoperatively (36), similar to the findings of Fang et al. Here, CALCA is linked to systemic inflammatory response syndrome.