Our published findings in NSCLC, mesothelioma (4) and ovarian (22) MPE reveal a profound degree of polarization dominated by near nM concentrations of IL-6/sIL6Rα, IL-8, IL10, VEGF, FGF2 and CXCL10. The gene discussed is CXCL10; the disease is non-small cell lung carcinoma.