Previous research has identified Notch3 as a diagnostic marker for cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) (32, 33), while DLL1 has shown utility in diagnosing tuberculous meningitis (12). This evidence concerns the gene DLL1 and cerebral arteriopathy with subcortical infarcts and leukoencephalopathy.