Other cytokines assessed were for the most part unchanged (Supplementary Figure 3) other than IL-6, IL-22, and KC (CXCL1) which were likewise increased in plasma of both C57BL/6 and TCRδ-/- mice with DSS colitis indicative of systemic inflammation (Supplementary Figures 3C, D). Here, CXCL1 is linked to colitis.