CD274 and bacterial infectious disease with sepsis: As none of the investigated bacteremia patients was diagnosed with septic shock and the majority of patients showed a substantial improvement in the course of the disease until the blood sample for RNA-AmpliSeq investigations was drawn, the lack of CD274 expression in the scrutinized patient’s monocytes is in line with the observed full responsiveness towards S. aureus stimulation ex vivo and the lack of expression of other tolerance marker.