It includes three age-dependent clinical phenotypes: neonatal intrahepatic cholestasis caused by citrin deficiency(NICCD), adult-onset type II citrullinemia (CTLN2) and failure to thrive and dyslipidemia caused by citrin deficiency (FTTDCD) between NICCD and CTLN2 stages (1). Here, SLC25A13 is linked to neonatal intrahepatic cholestasis due to citrin deficiency.