Subsequently, other FTO inhibitors, such as MO-I-500, FB23-2, R-2HG, CS1, and CS2, are also showed the antitumor effect on diverse cancers, including Alzheimer's disease (AD) 152, nasopharyngeal carcinoma 153, Breast Cancer 154, AML 155, 156, 157, cholangiocarcinoma 158, renal cell carcinoma 96. Here, FTO is linked to breast cancer.