PER1 and ischemic stroke: To confirm the expression levels of circadian clock genes during ischemic stroke and determine whether SR9009 affects circadian clock in the ischemic cortex of mice, the gene (Figures 6A–D) and protein (Figures 6E–H) expression levels of Rev-erbα, Bmal1, Clock and Per1 were investigated at 24 h after MCAO.