LAMP1 and infection: In 2-month-old mice, H7N7 at day 8 post-infection resulted in a significant increase in lysosome volume labeled with LAMP-1 in microglial cells in the CA1 subregion of the hippocampus [Δ121%, p = 0.02, two-way ANOVA Finfection(1, 18) = 6.05, p = 0.02, Figure 7B] of unvaccinated mice compared to control mice inoculated with PBS.