In addition, dexmedetomidine administration, BMI, male, preoperative use of NSAIDs, preoperative hemoglobin, preoperative albumin, preoperative eGFR, increased intraoperative infusion volume, increased intraoperative total fluid out, and intraoperative minimum MAP were independently associated with a reduced risk of postoperative AKI. This evidence concerns the gene ALB and acute kidney injury.