Among them, the JAK2/STAT3 pathway is a component of JAK/STAT signaling that is upregulated in a variety of tumor cells and is particularly involved in the development of some solid tumors through the regulation of tumor cell proliferation and apoptosis (Jiang et al., 2016; Iriki et al., 2017; Wu et al., 2017). The gene discussed is JAK2; the disease is neoplasm.