CXCR4 and metabolic dysfunction-associated steatohepatitis: A recent study demonstrated that the infusion of c-kit-positive liver sinusoidal endothelial cells (LSECs) improves homeostasis in the pericentral liver endothelium and diet-induced NASH in mice by impacting LSEC–macrophage–neutrophil crosstalk mediated by repressing C-X-C motif chemokine receptor 4 (CXCR4) transcription by CCAAT enhancer-binding protein α (CEBPA) (Duan et al., 2022).