Although PCDH7 is a member of the protocadherin family, which is a subfamily of cadherins known to regulate epithelial-to-mesenchymal transition (EMT) of tumor metastasis during cancer progression, the related study of the detailed mechanism by which PCDH7 affects colorectal cancer metastasis is too little and needs further investigation in CRC. The gene discussed is PCDH7; the disease is cancer.