PCDH7 and colorectal cancer: As anticipated, the protein expression of Mcl-1 was upregulated following PCDH7 overexpression in HCT116 cells and downregulated after PCDH7 knockdown in RKO cells, which may partially explain the anti-apoptotic effect exerted by PCDH7 on colorectal cancer cells (Figures 7A–C).