The 26.42% increase in the PINT% in the male–CTL–TS–WD group was significant compared to the male–CTL–WD group (p = .003), whereas in female rats, the PINT% did not show any significance (26.59%) in the CTL–TS–WD group, although a 16.3% increase was observed (Figure 3a,b). Here, LINC-PINT is linked to Wilson disease.