Second, one interpretation of all the findings presented so far may be that they do not actually contradict each other and may coexist in the following way: even though the interactions between TNF-ɑ or IL-1β and PCOS may not be genetic in origin, they may arise during the life of the female; in other words, the association may be acquired rather than hereditary. This evidence concerns the gene TNF and polycystic ovary syndrome.