Whether for intraprostatic pathologies, extraprostatic extensions, seminal vesicle involvement, or early changes in the bone PSMA PET/MRI has shown potential for improving diagnostic and prognostic performance in primary PCa as well as PCa biochemical recurrence (Eiber et al. 2016; Guberina et al. 2020). Here, FOLH1 is linked to posterior cortical atrophy.