To be specific, the incidence of hearing loss among patients carrying AG genotype at rs1050851 was 55.0%, which was much higher than that of 15.8% among patients carrying GG genotype (no AA genotype was observed).rs1050851 is a synonymous coding variant within the exon 2 of NFKBIA gene (Fig. 1B). The gene discussed is NFKBIA; the disease is hearing loss disorder.