Moreover, signatures of several downstream targets of c-MET signaling, such as MET Activates PTK2 Signaling, MET Promotes Cell Motility, and PI3K-AKT Signaling, were also enriched in the ASAP2-high HCC according to GSEA (Additional file 1: Fig. S6A). The gene discussed is ASAP2; the disease is hepatocellular carcinoma.