Moreover, DFS results also showed that increased CENPO expression was associated with poorer prognosis in ACC (p = 0.00033), KICH (p = 0.03), LIHC (p = 0.0081), LUAD (p = 0.014), SARC (p = 0.0093), UVM (p = 0.011), LGG (p = 0.02), SKCM (p = 0.042), and MESO (p = 0.08) (Fig. 3C and Additional file 2: Fig. S3B). This evidence concerns the gene CENPO and adrenal cortex carcinoma.