Furthermore, an increase in CENPO level was associated with poor overall survival (OS) in ACC (p = 0.0012), KICH (p = 0.0011), LIHC (p = 0.0015), LUAD (p = 0.0088), sarcoma (SARC; p = 0.0053), uveal melanoma (UVM; p = 0.0064), LGG (p = 8.4e-06), SKCM (p = 0.00041) and mesothelioma (MESO; p = 5.8e-05) (Fig. 3B and Additional file 2: Fig. S3A). Here, CENPO is linked to uveal melanoma.