The results showed that the high-cholesterol diet can significantly activate the jejunum mRNA levels of NPC1L1, ABCG5, ABCG8, ABCA1, and LXRα in the ApoE−/− + HF mice, but had no statistical change in the ACC, ACS, SREBP1, HMGCR, and LXRβ (Fig. 3A). The gene discussed is NR1H2; the disease is hydrops fetalis.