Four factors related to in-hospital MACCE in patients with STEMI were included in the multivariate logistic regression analysis, including the SHR (OR = 11.26, 95% CI: 3.05–55.21, P < 0.001), occurrence of arrhythmia (OR = 16.79, 95% CI: 2.72–328.46, P = 0.011), acute heart failure (OR = 14.35, 95% CI: 3.47–98.88, P = 0.001), and CRP (OR = 1.05, 95% CI: 1.02–1.09, P = 0.003). The gene discussed is CRP; the disease is cardiac arrhythmia.