RAD54L2 and renal cell carcinoma associated with Xp11.2 translocations/TFE3 gene fusions: Rad54 like 2 (Rad54l2) which might be one of key effector proteins of DNA damage mediated by estrogen was downregulated in numerous cancers, however, its role in epidemiological characteristics of Xp11.2 tRCC was needed to further study.