DNM1L and autosomal dominant centronuclear myopathy: This notion is also sustained by our identification of a mutation in Vps1 stalk region, I442G, corresponding to the human variant DNM2(V375G) causing centronuclear myopathy (Table 2), which displays a severe defect in autophagic flux but normal Atg9 transport to the PAS (Fig. 6, B, C and D).